R-454B is an alternative HFC/HFO blended refrigerant designed for modern air conditioning systems, serving as a replacement for R-410A. It offers excellent cooling performance while significantly reducing environmental impact due to its lower Global Warming Potential (GWP) and zero ozone depletion (ODP=0). Specifically, its GWP is approximately 75% lower than R-410A. The blend consists of approximately 68.9% R-32 (Difluoromethane) and 31.1% R-1234yf (Tetrafluoropropene), forming a near-azeotropic mixture that ensures stable performance characteristics. Key features include high cooling efficiency comparable to R-410A and suitability for new-generation air conditioning systems focused on energy efficiency and environmental sustainability. Classified as a Gas under pressure and having a flammability class of A2L (mildly flammable), its installation, charging, and maintenance must be performed by qualified professionals in compliance with strict safety standards. This next-generation refrigerant effectively balances performance, safety, and environmental responsibility, making it well-suited for long-term greenhouse gas emission reduction in air conditioning applications.